Journal of the Korean Ophthalmological Society 2000;41(1):12-17.
Published online January 1, 2000.
The Lysozymal Concentration in Tear Film of Contact Lens Us ers.
Beak Ran Song, Do Kyun Kim, Do Seok Byon
Department of Ophthalmology, College of Medicine, Inha University.
콘택트 렌즈 사용자의 누액내 리소자임 농도변화
송백란(Beak Ran Song),김도균(Do Kyun Kim),변도석(Do Seok Byon)
Abstract
The contact lens wearers are exposed to the risk of permanent visual dysfunction due to various ocular diseases, especially corneal infections. And ocular disease of contact lens wearers are reported to be closely related to the biochemical alterations of tear film. To compare the lysozyme concentration of reflex tear in normal subjects and contact lens wearers, the tear was collected from 38 eyes of 38 normal subjects and 34 eyes of 34 contact lens wearers. The age of the subjects were between 20 to 39 years. The mean concentration of tear lysozyme were 3.55 +/-0.9 6 milligram/milliliter in normal subjects and 3.66 +/-1.02 milligram/milliliter in contact lens wearers. There was no statisti-cally significant difference between the two groups[p>0.05 ]. Though contact lens wearing does not decrease the concentration of tear lysozyme, it seems that this protein serves as a mediator of corneal infection by adhering to the surface of the contact lenses.
Key Words: Contact lens;Corneal infection;Lysozyme


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