Apnea Associated with General Anesthesia in the Surgical Treatment of Retinopathy of Prematurity and its Risk Factors.

Kang, Kyoung Bok; Seo, Jong Mo; Yu, Young Suk; Kim, Hee Soo; Kim, Chong Sung; Kim, Beyong Il; Choi, Jung Hwan

Original Article

Journal of the Korean Ophthalmological Society 2000;41(2):488-494.
Published online February 1, 2000.

Apnea Associated with General Anesthesia in the Surgical Treatment of Retinopathy of Prematurity and its Risk Factors.

Kyoung Bok Kang, Jong Mo Seo, Young Suk Yu, Hee Soo Kim, Chong Sung Kim, Beyong Il Kim, Jung Hwan Choi

¹Department of Ophthalmology, College of Medicine, Seoul National University.
²Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea.

미숙아망막병증의 수술적 치료 후 전신마취와 관련된 무호흡

강경복(Kyoung Bok Kang),서종모(Jong Mo Seo),유영석(Young Suk Yu),김희수(Hee Soo Kim),김종성(Chong Sung Kim),김병일(Beyong Il Kim),최중환(Jung Hwan Choi)

Abstract

We evaluated the relationship between preoperative risk factors[gestational age, birth weight, postconceptual age and weight at operation, duration of operation, duration of anesthesia, abnormalities in neurosonogram, bronchopulmonary dysplasia]and apnea with or without bradycardia, for which mechanical ventilation was necessary after general anesthesia in the surgical treatment of retinopathy of prematurity[ROP]. Thirty-eight patients [21%]developed apnea and thirteen patients[7%]had bradycardia out of 183 patients. Retrospective study was performed and risk factors were analyzed by logistic regression. Gestational age, birth weight, postconceptual age and weight at operation and bronchopulmonary dysplasia showed the positive correlation with postanesthetic apnea and bradycardia. Duration of operation showed the positive correlation with postanesthetic apnea but not with postanesthetic bradycardia. In logistic regression without confoundings, weight at operation and bronchopulmonary dysplasia were correlated with postanesthetic apnea. Receiver operating characteristic curve analysis revealed that patients with weight under 2, 600gm at operation suffered from apnea more frequently than those with weight over 2, 600gm. In conclusion, patients with weight under 2600gm or bronchopulmonary dysplasia are at greater risk for postanesthetic apnea and optimal pre-and postanesthetic management should be prepared for these patients.

Key Words: Postanesthetic apnea;Retinopathy of Prematurity