A Case of Optic Nerve Infiltration of Acute Lymphocytic Leukemia.

Park, Yoo Kyung; Jun, Roo Min; Ahn, Chung Sook

Case Report

Journal of the Korean Ophthalmological Society 2000;41(9):2008-2012.
Published online September 1, 2000.

A Case of Optic Nerve Infiltration of Acute Lymphocytic Leukemia.

Yoo Kyung Park, Roo Min Jun, Chung Sook Ahn

Department of Ophthalmology, Ewha Women's University, Mokdong Hospital, #911-1 Mokdong, Yangcheon-ku, Seoul, 158-056, Korea.

급성 림프구성 백혈병의 시신경 침윤 1 례

전루민(Roo Min Jun),안정숙(Chung Sook Ahn),박유경(Yoo Kyung Park)

Abstract

Leukemia is a common malignancy in childhood and has various associated ocular manifestations. Clinically, retina is the most commonly involved site and papilledema may be observed due to either direct infiltration or CNS involvement of leukemia. We have experienced a case of mass-like leukemic infiltration in retina and optic nerve in a 16-year-old ALL patient who presented with sudden reduction of visual acuity. With systemic chemotherapy, intrathecal methotrexate and radiotherapy, visual acuity and fundus findings improved. We report this unusual condition with a review of previous report.

Key Words: ALL;Mass-like infiltration;Optic nerve;Radiation