Journal of the Korean Ophthalmological Society 1999;40(5):1276-1280.
Published online May 1, 1999.
The Effects of Pa n retinal Photocoagulation on Macular Microcirculation in Diabetic Retinopathy(Short term follow up).
Jin Ho Woo, Jang Won Heo, Hee Seong Yoon
Department of Ophthalmology, College of Medicine, Dong-A University.
당뇨망막병증에서 범망막광응고술이 황반부 미세순환에 미치는 영향 ( 단기 추적 관찰 )
우진호(Jin Ho Woo),허장원(Jang Won Heo),윤희성(Hee Seong Yoon)
Abstract
We investigated the effects of panretinal photocoagulation (PRP)on macular microcirculation in diabetic retinopathy. PRP using argon blue green laser was performed in 23 eyes of 15 patients with early proliferative diabetic etinopathy and very severe nonproliferative diabetic retinopathy without significant macular edema. The changes in volume, flow, velocity of macular microcirculation were measured before PRP, 1 hour, 1 day, 1 week, and 1 month following PRP, using Heidelberg Retina Flowmeter(HRF). Mean volume, flow, velocity of macular microcirculation decreased to a maximal degree 1 hour following PRP, from 14.87+/-0.40, 387.45 +/-101.40, 1.40+/-0.28(before PRP)to 12.44+/-1.39, 347. 33+/-100.39, 1.27+/-0.34(p<0.05). From 1hour to 1 month after PRP, macular microcirculation gradually increased. However, throughout this period, all parameters of macular microcirculation remained lower than pre-PRP level(p<0.05). Our study suggests that panretinal photocoagulation reduces the macular microcirculation in diabetic retinopathy.
Key Words: Diabetic retinopathy;Heidelberg retina flowmeter;Macular microcirculation;Panretinal photocoagulation


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