Journal of the Korean Ophthalmological Society 1999;40(5):1352-1361.
Published online May 1, 1999.
The Effect of Topical Antiglaucomatous Medication on the Outcome of Trabeculectomy.
Jun Sung Park, Il Suk Kang, Jong Heun Lee
Department of Ophthalmology, School of Medicine, Sungkyunkwan University, Masan Samsung Hospital.
술전 항녹내장 점안제 투여가 섬유주절제술에 미치는 영향
박준성(Jun Sung Park),강일석(Il Suk Kang),이종흔(Jong Heun Lee)
Abstract
The purpose of this study was to determine whether preoperative topical antiglaucomatous therapy influences the outcome of subsequent trabeculectomy. We investigated 50 eyes of 36 patients with primary open anlge glaucoma(POAG)and 86 eyes of 77 patients with primary angle closure glaucoma (PACG), who had undergone trabeculectomy. All the patients had received topical antiglaucomatous therapy preoperatively and had been followed up for at least 6 months postoperatively. Both groups, POAG and PACG were divided into two subgroups according to the duration of preoperative antiglaucomatous therapy: (a)for less than 1 month and (b)for more than 6 months. The criterion for success was maintenance of postoperative intraocular pressure(IOP)below 21 mmHg without medication. The rates of success were compared at 1 week, 1 month, 3 months, and 6 months postoperatively. In POAG patients, the overall success rate was clinically significantly higher in subgroup (a)than in subgroup (b)(P<0.05). The success rate in subgroup (a)of POAG patients remained higher irrespective of class of antiglaucomatous medications(P<0.05). In PACG patients, the success rate was also higher in subgroup A, but it failed to reach clinical significance. Postoperative mean IOP was slightly lower in subgroup (a)of all the participants, but it was not clinically significant. Our study suggests that long-term use topical antiglaucoma medications can affect adversely the result of filtering surgery in POAG.
Key Words: Preoperative antiglaucomatous topical therapy;Trabeculectomy;Primary open angle glaucoma;Primary angle closure glaucoma


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