Journal of the Korean Ophthalmological Society 1999;40(7):1893-1902.
Published online July 1, 1999.
An Electroretinographic Changes of Laser-induced Experimental Branch Retinal Vein Occlusion in the Rabbits.
Hokyun Cho, Jaesoon Kim, Youngjin Kim
Department of Ophthalmology, College of Medicine, Chung-Ang University, Seoul, Korea.
토끼에서 레이저에 의한 실험적 분지망막정맥폐쇄가 망막전위도에 미치는 영향
조호균(Ho Kyun Cho),김재순(Jae Soon Kim),김영진(Young Jin Kim)
Abstract
To verify whether laser-induced branch retinal vein occlusion in the rabbit can be used as the experimental model for the human study. The temporal retinal vein of the right eye was occluded with argon laser photocoagulator with parameters of 500 micrometerspot size, 0.2 second duration, 150-200 microWatt power in twelve pigmented rabbits. The left eye was used as a control. An electroretinogram was taken before and 1,3,7,15 and 28 days after vein occlusion. B/a ratio and oscillatory potentials increased in the eyes with occluded veins. Comparing the pre-occlusion values with those of post-occlusion, the changes were not statistically significant. But differences between the values of right and those of left eye were significant. We can suppose that the discrepancies may result from the difference in timing of examination. In conclusion, the rabbit model of laser-induced experimental branch retinal vein occlusion may not be adequate for the study of clinical branch retinal vein occlusion.
Key Words: Branch retinal vein occlustion;Electroretinogram;Experimental;Laser-induced;Rabbit


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