Journal of the Korean Ophthalmological Society 1997;38(12):2141-2146.
Published online December 1, 1997.
Clinical Studies on the Relation of HLA B-27 and Uveitis.
Dong Yeon Lee, Jung Chul Shin, Jun Kiu Choe, Yea Shu Park
1Department of Ophthalmology, College of Medicine, Hanyang University Hospital, Seoul, Korea.
2Department of Orthopedic Surgery, College of Medicine, Hanyang University Hospital, Seoul, Korea.
HLA B-27 과 포도막염의 관계에 대한 임상적 고찰
이동연(Dong Yeon Lee),신정철(Jung Chul Shin),최준규(Jun Kiu Choe),박예수(Yea Shu Park)
Abstract
It is well known that the incidence of anterior uveitis is about 20-40% in HLA B-27 associated joint diseases, and especially common in male between the ages of 20 and 40. However, there is no study of the epidermiology and clinical features of it in Korea. The authors studied to know the incidence and clinical feature of uveitis in HLA B-27 associated joint diseases in Korea. We reviewed the records of 543 patients with HLA B-27 associated joint diseases, visited our rheumatoid center from March 1991 to August 1996. All patients were subjected to routine laboratory examinations; i.e., blood cell count, erythrocyte sedimentations rate, C reactive protein, rheumatoid factor, anti-nuclear antibody, and x-ray of the lumbosacral spine & sacro-iliac joints. 462 patientsout of 543 patients with HLA B-27 associated joint diseases had spondyloarthropathy. Anterior uveitis occurred in 32 patients (6.9%) among these 462 spondyloarthropathy patients. Clinical characteristics of the uveitis were male predominant (23/32) anterior uveitis (32/32), and unilateral (31/32).
Key Words: HLA B-27;arthritis;uveitis


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