Effect of Excimer Laser Photorefractive Keratectomy on Density and Morphology of Corneal Endothelial Cells. |
Won Ryang Wee, Kayoung Yi, Myung Hee Lee, Jin Ho Chang, Jin Hak Lee |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. 2Department of Ophthalmology, Seoul City Hospital, Seoul, Korea. |
엑시머레이저 굴절교정각막절제술이 각막내피세포의 밀도와 형태에 미치는 영향 |
이가영(Kayoung Yi),위원량(Won Ryang Wee),이명희(Myung Hee Lee),장진호(Jin Ho Chang),이진학(Jin Hak Lee) |
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Abstract |
We investigated the effect of excimer laser photorefractive keratectomy (PRK) on corneal endothelium in both contact lens wearer and non-wearer. Myopes (-3.0D~-9.5D) who underwent excimer laser PRK at Seoul National University Hospital from March to September 1996 were enrolled in this study. Six patients of 9 eyes had no history of contact lens wearing or discontinued wearing contact lens at least 1 year preoperatively (contact lens non-wearers) and 10 patients of 17 eyes wore their contact lenses until 4 weeks before surgery (contact lens wearers). The cnetral corneal endothelial cell density and morphology were evaluated by specular microscopy before and 1week, 3 and 6 months after surgery. In contact lens non-wearer group, no significant postoperative change was observed. But in contact lens wearer group, significnat increase of density and significant decrease fo pleopmorphism index were noted at postoperative 3 and 6 months, respectively. These results suggest that excimer laser PRK does not affect central corneal endothelium and the discontinuation of wearing contact lens may induce postoperative change of corneal endothelim. |
Key Words:
Excimer laser photorefractive keratectomy;Corneal endothelium;Contact lens |
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