A Conjunctival Malignant Melanoma Involving the Cornea.

Moon, Jung Sig; Lee, Ja Young; Chung, Sung Kun; Yu, Young Suk

Original Article

Journal of the Korean Ophthalmological Society 1998;39(6):1035-1039.
Published online January 1, 2001.

A Conjunctival Malignant Melanoma Involving the Cornea.

Jung Sig Moon, Ja Young Lee, Sung Kun Chung, Young Suk Yu

Department of Ophthalmology, School of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

In a case of conjunctival malignant melanoma involving the cornea, we evaluated the findings of H,E, Fontana-Masson, S-100 protein, HMB 45 stain after the localized excision in 39 years old male patient. B-scan ultrasonography, orbit, MRI, Ga citrate scanning and bone scan showed no metastasis to the intraocular tissue, orbital adnexae and other organs. In H-E stain, spindle cells containing melanin pigment which was growing diffusely underneath the conjunctival epithelium could be seen. Fontana-Masson and S-100 protein staining resulted in diffusely positive findings, Therefore we could diagnose as 8 spindle B type malignant m.elanom.a. By histopathological examination, in a case of confirmed spindle B type COunctival malignant melanoma involving the cornea, good result, could be obtained by localized excision followed by 11 months.

Key Words: Conjunctival malignant melanoma;Fontana-Masson stain;HMB 45 stain;S-100 protein stain