Journal of the Korean Ophthalmological Society 1992;33(11):1088-1092.
Published online November 1, 1992.
Electronmicroscopic Study of the Effect of Hexamethonium on Serous Choriretinopathy in Rabbits.
Hyeon Seok Lee, Ho Kyung Lee, Jin Hyung Yoo
Department of Ophthalmology, In Je University Paik, Hospital, Korea.
교감신경 차단제가 실험적 장액성 맥락망막염에 미치는 영향 - 전자 현미경적 연구 -
이현석(Hyeon Seok Lee),이호경(Ho Kyung Lee),유진형(Jin Hyung Yoo)
Abstract
Stress has been regrarded as one of the causes of central serous chorioretinopathy. We studied the effect of Hexamethonium (ganglionic blocking agent) on experimentaI serous chorioretinopathy following epinephrine injection in rabbits. In group 1, we injected the 0.1 % epinephrine into the rabbits through IV route for 10 days and in group 2, we addited Hexamethonium subcutaneously prior to injection of the epinephrine same term of gorup 1. We could find slight histological changes in gorup 2 as com paired with group 1, which produced serous chorioretinopathy, under the electronmicroscopic study so we would expect the preventive effect of Hexamethonium on the stress-induced serous chorioretinopathy.
Key Words: Electronmicroscope;Epinephrine;Hexamethonium;Serous chorioretinopathy


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