Clinical Analysis of Vogt- Koyanagi-Harada Disease.

Woo, Kyung In; Chung, Hum

Original Article

Journal of the Korean Ophthalmological Society 1993;34(1):26-34.
Published online January 1, 1993.

Clinical Analysis of Vogt- Koyanagi-Harada Disease.

Kyung In Woo, Hum Chung

Department of Ophthalmology, College of Medicine, Seoul National UniversIty, Korea.

Vogt - Koyanagi - Harada 병의 임상 분석

우경인(Kyung In Woo),정흠(Hum Chung)

Abstract

Clinical records of 41 patients with Vogt-Koyanagi-Harada disease (VKH disease) who had visited Seoul National University Hospital from 1986 to 1990 were reviewed. Twenty one patients were men and twenty patients were women. Extraocular manifestations included headache (64%), alopecia (34%), poliosis (24%), vitligo (12%), tinnitus (14%), and dysacousia (14%). Arden ratios in electro-oculogram (EOG) were low in the early stages of disease, and became improved with regaining vision. The amplitudes of electroretinogram (ERG), which were low in the early stage, recovered during medication in many cases. Visual prognosis was better if patients were treated with systemic steroid from the beginning. Factors contributing to recurrent or persistent inflammation despite of treatment included numerous extraocular manifestations and delayed treatment.

Key Words: Electroretinogram;Electro-oculogram;Visual acuity;Vogt-Koyanagi-Harada disease