| The Chantres of ERG b-wave and Oscillatory Potential in White Rat during Dark Adaptation. |
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Byoung Woo Sohn, Jung Woo Kim, Jae Myung Kim |
1Department of Ophthalmology, Kangdong Sacred Heart Hospital College of Medicine, Hallym University, Seoul, Korea.
2Department of Ophthalmology, College of Medicine, Kyung Hee University, Seoul, Korea. |
| 백색쥐에서의 암순응 시간에 따른 망막전위도 b - 파와 율동양파의 변화 |
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손병우(Byoung Woo Sohn),김정우(Jung Woo Kim),김재명(Jae Myung Kim) |
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| Abstract |
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We studied changes of b-wave and oscillatory potential in ERG test during dark adaptation in white rats for the purpose of using it in experimental disease-group and studying difference in man. For this we performed ERG test on normal 14 S-D (Sprague-Dawley) rats (28 eyes) during dark adaptation. The implicit time of a-wave and b-wave was shortend during dark adaptation. The b-wave and oscillatory potential rapidly increased by 20 and 30 minutes during dark adaptation: in b-wave, these values were 425.89 +/- 141.15 micro v, 473.65 +/- 130.35 micro v respectively, and in oscillatory potential, 110.56 +/- 54.82 micro v, 126.27 +/- 48.24 micro v respectively. After then, these were slightly increased. This results reveal that dark adaptatin in ERG test using rats needs sufficient time from 20 minutes to 30 minutes in similar to man. The oscillatory potential in white rat had three components with 1] light stimulus and the increase of amplitude of oscillatory potential was similar to that of b-wave during dark adaptation. But we should consider that the decreased cone function of white rat was different from that of man, that amplitude of b-wave was continously increased without the break point of early 6 minutes, and that the implicit time of b-wave was continously decreased after 10 minute during dark adaptation, when we use rat. |
| Key Words:
ERG;Dark adaptation;Rat |
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