Journal of the Korean Ophthalmological Society 1990;31(5):623-633.
Published online May 1, 1990.
The Effect of the Nd:YAG Laser on the Rabbit Retina.
Young Cheol Jean, Oh Woong Kwon
Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Nd : YAG laser 가 가토 망막에 미치는 영향
전영철(Young Cheol Jeon),권오웅(Oh Woong Kwon)
The effect of the Nd:YAG laser on the rabbit retina was evaluated with fundus photography, light microscopy and transmission electron microscopy(TEM), and compared with the effect of the Argon laser. Fundus photography was performed at 2 days, 4 days, 7 days, 14 days, 29 days and 49 days after treatment. The enucleated retina was examined by light microscopy and TEM. In YAG treated eye, laser reaction was not found at 0.5mJ level but laser reaction(G2-3) was found at 1.5mJ level. Laser reaction(G3-4) with expulsive bleeding was found at 2.5 and 3.5mJ level. Bleeding was seemed to be originated from the choroidal layer. 2 days after treatment, hemorrhage was sustained but bleeding was not continued. 7 days after treatment, hemorrhage was completely absorbed. In Argon treated eye, photocoagulation burns was well formed without and bleeding. In pathologic examination of YAG treated eye, full thickness disruption of the retina amd Bruch's membrane and replacement of these layers with fibrous scar tissue were revealed at 2.5 and 3.5mJ level. In 1.5mJ energy level of the YAG laser and Argon laser irradiation, the outer half of the retina, RPE and Bruch's membrane appeared to be pridominantely affected than the inner half of the retina. The extent and character of his to pathology in Argon treated lesion was not so different from that of the YAG laser 1.5mJ lesion.
Key Words: clinical;histopathology;neodymium: YAG laser;retinal irradiation or photocoagulation

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