The 13q14 Deletion in Retinoblastoma.

Kim, Ji Won; Chung, Sung Kun; Chung, Sang Moon

Original Article

Journal of the Korean Ophthalmological Society 1991;32(12):1076-1079.
Published online December 1, 1991.

The 13q14 Deletion in Retinoblastoma.

Ji Won Kim, Sung Kun Chung, Sang Moon Chung

Department of Ophthalmology, St. Mary,s Hospital Catholic University Medical College, Seoul, Korea.

망막아세포종에 있어서 염색체 13q14 결손

김지원(Ji Won Kim),정성근(Sung Kun Chung),정상문(Sang Moon Chung)

Abstract

Retinoblastoma is the most common intraocular malignant tumor in children. Retinoblastoma is divided two groups, hereditary and non-hereditary. Hereditary retinoblastoma is relakd to chormosomal abnormalities. By banding technique of somatic chromosome in retinoblastoma, deletion of chromosome 13q14 is found, but it has not been reported domestically. We experienced two cases of retinoblastoma with chromosome 13q14 deletion.

Key Words: Banding technique;Chromosome 13q14 deletion;Retinoblastoma