The Antibacterial Sensitivity of Domestic Topical Antibiotics: in vitro test.

Lee, Jin Hak; Jung, Yeon Chul

Original Article

Journal of the Korean Ophthalmological Society 1988;29(5):801-804.
Published online May 1, 1988.

The Antibacterial Sensitivity of Domestic Topical Antibiotics: in vitro test.

Jin Hak Lee, Yeon Chul Jung

Department of Ophthalmology, College of Medicine, Seoul National Uuiversity, Seoul, Korea.

국산 점안 항생제의 항균효과 - In Vitro -

이진학(Jin Hak Lee),정연철(Yeon Chul Jung)

Abstract

The antibacterial activity of 11 domestic topical antibiotic eye drops were examed by use of Reddish method, in vitro test. 5 clinical strains which were recovered as common pathogens of corneal ulcer, were inoculated into the diluted antibiotics added with 1% human serum, and 0.01 ml were plated for bacterial survival at 0.5, 1, 2, 4, 8, 16. and 24 hours. Our result showed that gentamicin eye drops effective in Gram negative strains and penicil-line and cefazoline eye drops were effective in Gram positive strains. These results indicated that gentamicin and cefzolin eye drops in combination would be covered the common ocular pathogenic bacteria.