Journal of the Korean Ophthalmological Society 1988;29(6):1081-1090.
Published online June 1, 1988.
Effect of the Viscoelastic Substance on Surgery of the Extraocular Muscles in Rabbit: 1. Histopathologic Study by a Light Microscope.
Young Bae Rho, Kyung Won Yoo, Jae Bong Kim, Kang Suk Suh
1Department of Ophthalmology, School of Medicine, Pusan National University, Pusan, Korea.
2Department of Anatomy, School of Medicine, Pusan National University, Pusan, Korea.
3Department of Surgical Anatomy, School of Medicine, Pusan National University, Pusan, Korea.
점액탄성물질 ( Viscoelastic Substance ) 이 가토 외안근에 미치는 영향 - 제 1 보 : 경시적 변화 -
노영배(Young Bae Rho),유경원(Kyung Won Yoo),김재봉(Jae Bong Kim),서강석(Kang Suk Suh)
Abstract
We evaluated histopathologically the effect of the viscoelastic substance on surgery of the extraocular muscle in the 26 rabbits with 1. 6-2. 5kg of weight. The viscoelastic substances were 1% sodium hyaluronate(Healon) and 2% hydroxypropyl methylcellulose(Methocel), which were introduced between the extraocular muscle and its adjacent tissue on surgery. The rabbits were categorized by group 1(the rabbits with Healon), group 2(with Methocel), and group 3(with normal saline as control). These rabbits were enuclated at 3rd, 7th, 14th, 28th and 56th day following operations, and the eyes were fixed in 2.5% glutaraldehyde solution. The tissue was stained with hematoxylin-eosin and Masson's trichrome, and examined under a light microscope. The results were as follows: 1. In the first group(Healon), the tissue adhesion and degeneration of the muscle were milder than those of control(saline) group. 2. The changes in second group(Methocel) was milder than in the first group and more severe than in control group. 3. It is concluded that 2% Methocel can be used clinically in the surgery of the extraocular muscle.
TOOLS
METRICS Graph View
  • 363 View
  • 0 Download
Related articles


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos08@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next