Journal of the Korean Ophthalmological Society 1989;30(5):749-754.
Published online May 1, 1989.
The Influence of Phenylephrine, Mydrin-P(R) and Cyclopentolate on Intraocular Pressure Elevation.
Moon Joo Lee, Young Jae Hong
Department of Ophthalmology, Yonsei University, College of Medicine, Seoul, Korea.
Phenylephrine , Mydrin - P(R) 와 Cyclopentolate 의 안압상승 효과
이문주(Moon Joo Lee),홍영재(Young Jae Hong)
Abstract
Pharmacological mydriasis can cause an acute elevation of intraocular pressure without obstruction of angle. A prospective study of 80 normal Korean subjects(149 eyes) and 20 Korean primary open angle glaucoma patients(49 eyes) was performed in order to obtain and compare effects on intraocular pressure, pupil size and aqueous floater by phenylephrine, Mydrin-P(R) and cyclopentolate and to investigate wheather intraocular pressure elevation occurs also in Korean eyes after pupil dilation. Significant pressure elevation(6mmHg or more) was rare in normal subjects while incidence of 25% with Mydrin-P(R) and 50% with cyclopentolate occurred in primary open angle glaucoma patients. Thus, stronger cyclopegics induced intraocular pressure elevation more frequently. Statistically significant correlation between intraocular pressure elevation and aqueous floater did not exist in primary open angle glaucoma patients but only existed with cyclopentolate in normal subjects. Maximum mydriasis by phenylephrine, Mydrin-P(R) and cyclopentolate occurred in 60, 90 and 90 minutes respectively. There is a potential hazard of routine dilation of eyes with cycloplegic agents in primary open angle glaucoma patients in both Korean and occidental eyes.
Key Words: aqueous floater;cycloplegic;intraocular pressure;mydriatic;primary open angle glaucoma


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos08@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next