| Vitrectomy versus Intravitreal Antibiotic Injection to Treat Acute Endophthalmitis Developing after Cataract Surgery. |
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Jung Yup Kim, Joo Eun Lee, Kang Yeun Pak |
1Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. pky0402@naver.com
2J Eye Center, Busan, Korea. |
| 백내장수술 후 발생한 급성 안내염에서 유리체절제술과 유리체내 항생제 주사 치료 효과 비교 |
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김중엽1⋅이주은2⋅박강윤1 |
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인제대학교 의과대학 해운대백병원 안과학교실1, 제승연 안과2 |
Correspondence:
Kang Yeun Pak,
Email: pky0402@naver.com
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Received: 28 September 2017 • Revised: 30 October 2017 • Accepted: 1 January 2018 |
| Abstract |
PURPOSE
To compare the therapeutic efficacy of vitrectomy plus intravitreal antibiotic injection (vitrectomy group) with intravitreal antibiotic injection alone (antibiotic group) for eyes with acute endophthalmitis developed after cataract surgery with visual acuity of hand motion or better. METHODS: In this retrospective chart review, we compared the visual acuities of 10 eyes of a vitrectomy group and 17 eyes of an antibiotic group. RESULTS: We found no significant differences between the two groups in terms of age, comorbidities (diabetes, hypertension), time of symptom onset, time of diagnosis, type of systemic antibiotic prescribed, or positive culture rate. Mean baseline best-corrected visual acuity (BCVA) was similar in the two groups (2.17 vs. 1.96 logMAR; p = 0.60). Both groups exhibited significant improvements in mean BCVA after 2 months: from 2.17 to 0.81 logMAR in the vitrectomy group (p = 0.01) and from 1.96 to 0.76 logMAR in the antibiotic group (p = 0.002), but the final BCVA did not differ significantly between the two groups (0.81 vs. 0.76 logMAR, p = 0.75). CONCLUSIONS: Both vitrectomy combined with intravitreal antibiotic injection and intravitreal antibiotic injection alone significantly improved visual acuity; the final BCVA did not differ between the two groups. Intravitreal antibiotic injection alone may be an effective first-line treatment for endophthalmitis in patients with initial visual acuity of hand motion or better. |
| Key Words:
Acute endophthalmitis;Cataract surgery;Intravitreal antibiotic injection;Vitrectomy |
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