J Korean Ophthalmol Soc > Volume 59(6); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(6):537-542.
DOI: https://doi.org/10.3341/jkos.2018.59.6.537    Published online June 15, 2018.
Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Healthy Koreans.
Youna Choi, Byung Joo Cho
Department of Ophthalmology, Konkuk University School of Medicine, Seoul, Korea. bjcho@kuh.ac.kr
한국인에서의 빛간섭단층촬영기를 이용한 망막신경섬유층 두께 분석
건국대학교 의학전문대학원 안과학교실
Correspondence:  Byung Joo Cho,
Email: bjcho@kuh.ac.kr
Received: 20 July 2017   • Revised: 31 March 2018   • Accepted: 28 May 2018
To determine normal retinal nerve fiber layer (RNFL) thickness by age and to investigate the relationships of the RNFL with clinical variables using spectral domain optical coherence tomography (SD-OCT) in healthy Koreans. METHODS: The peripapillary RNFL thicknesses were measured around the optic disc using consecutive circular B-scans with 3.5 mm diameter and automatically calculated using a SD-OCT. RESULTS: Three hundreds fifty-two eyes of 205 healthy subjects were included in the study and RNFL thickness were measured by SD-OCT. Overall average RNFL thickness was 100.2 ± 10.9 µm, and significantly and negatively correlated with age (r = −0.164, p = 0.002). The overall average RNFL thickness decrease per decade was 0.8 µm (95% confidence interval, −0.3 to −1.3, p = 0.019). Mean RNFL thickness of each quadrant was significantly correlated with axial length except in the superior quadrant. CONCLUSIONS: This study describes the normal RNFL thickness values of Koreans as determined by SD-OCT. Furthermore, age was found to be correlated with normal RNFL thickness, however age-related changes were not uniform across every region.
Key Words: Axial length;Cup-to-disc ratio;Korean;Retinal nerve fiber layer;Spectral domain optical coherence tomography

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