J Korean Ophthalmol Soc > Volume 59(11); 2018 > Article
Journal of the Korean Ophthalmological Society 2018;59(11):1077-1081.
DOI: https://doi.org/10.3341/jkos.2018.59.11.1077    Published online November 15, 2018.
Two Cases of Corneal Edema Due to Vaporized Amine.
Yousook Hwang, Yang Kyung Cho
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. yangkyeung@hanmail.net
기화된 아민에 의한 각막부종 2예
가톨릭대학교 의과대학 안과 및 시과학교실
Correspondence:  Yang Kyung Cho,
Email: yangkyeung@hanmail.net
Received: 14 June 2018   • Revised: 6 August 2018   • Accepted: 30 October 2018
We report two cases of corneal edema in patients who presented with bilateral blurry vision due to vaporized amines while working in a polyurethane processing plant. CASE SUMMARY: A 28-year-old male presented with bilateral blurred vision. His work involved solidifying polyurethane liquid and he often found himself exposed to polyurethane heat and gas. On examination, the patient's uncorrected visual acuity (UCVA) was 20/40 (right) and 30/50 (left). A slit lamp examination revealed subepithelial microbullae in both eyes. The central corneal thickness (CCT) was also increased in both eyes, measuring 698 µm (right) and 672 µm (left). After prescribing 0.5% moxifloxacin and, 1% fluorometholone eye drops for 3 days in both eyes, the UCVA recovered to 20/40 (right) and 20/20 (left). The CCT decreased to 644 µm (right) and 651 µm (left), and the microbullae improved significantly in the left eye. The second patient was a 34-year-old female who presented with bilateral decreased visual acuity while at work. She worked in a factory that produced car seat filling. Her UCVA was 20/25 (right) and 20/20 (left). The CCT by specular microscopy was 537 µm (right) and 541 µm (left). On slit lamp examination, both eyes demonstrated bilateral central subepithelial edema. The patient did not attend any follow-up outpatient appointments after the initial presentation. CONCLUSIONS: Exposure to vaporized amines such as polyurethane may causereversible corneal toxicityeven without direct contact. Further consideration should be given to ocular safety and protection from amine compounds in the industrial field.
Key Words: Corneal edema;Dimethylethylamine;Polyurethane foam;Vapor

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