J Korean Ophthalmol Soc > Volume 56(1); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(1):148-153.
DOI: https://doi.org/10.3341/jkos.2015.56.1.148    Published online January 15, 2015.
A Case of Acute Incomitant Esotropia Associated with Wernike's Encephalopathy.
Moon Won Hwang, Sung Hyuk Moon
1Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. koils79@naver.com
2Therapeutics Center for Ocular Neovascular Disease, Busan, Korea.
베르니케 뇌병증과 연관된 급성 불일치 내사시 1예
Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine1, Busan, Korea
Therapeutics Center for Ocular Neovascular Disease2, Busan, Korea
We report a case of an acute incomitant esotropia with Wernike's encephalopathy. CASE SUMMARY: A 64-year-old male visited our hospital because of diplopia lasting a week. He was a chronic alcoholic drinking two bottles of makgeolli daily and eating little for a month. He showed -2 underaction of bilateral lateral rectus muscles and 45 prism diopters of esotropia at the primary position at the first visit. He had ataxia and mild cognitive impairment. There were high signal intensities in the periaqueductal area and mammillary bodies in the brain fluid attenuated inversion recovery magnetic resonance image. He was diagnosed with Wernike's encephalopathy clinically and was immediately treated with intravenous thiamine. He showed -0.5 underaction of bilateral lateral muscles and 8 prism diopters of esotropia at the primary position 3 days after thiamine treatment. CONCLUSIONS: Wernicke's encephalopathy is a medical emergency. If diagnosis and treatment are delayed, patients may have neurological sequelae that can lead to death. Esotropia and diplopia can be the presenting manifestations in Wernike's syndrome without other symptoms. In taking patient histories, physicians should ask about alcohol consumption and low food intake because of the possibility of acute incomitant esotropia associated with Wernicke's encephalopathy.
Key Words: Incomitant esotropia;Thiamine (vitamin B1);Wernicke's encephalopathy

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