J Korean Ophthalmol Soc > Volume 55(7); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(7):1017-1023.
DOI: https://doi.org/10.3341/jkos.2014.55.7.1017    Published online July 15, 2014.
Peripheral Vascular Leakage Findings of Asymptomatic Eyes Based on Fluorescein Angiography.
Sang Hyup Lee, Yong Un Shin, Byung Ro Lee, Myung Kyoo Ko
1Department of Ophthalmology, Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Korea. stynel@nate.com
2Department of Ophthalmology, Presbyterian Medical Center, Jeonju, Korea.
무증상안의 형광안저촬영에서 관찰되는 주변부망막의 혈관성 형광누출
이상협1⋅신용운1⋅이병로1⋅고명규2
Department of Ophthalmology, Hanyang University Medical Center, Hanyang University College of Medicine1, Seoul, Korea Department of Ophthalmology, Presbyterian Medical Center2, Jeonju, Korea
Abstract
PURPOSE
To report peripheral vascular retinal leakage findings of asymptomatic eyes based on fluorescein angiography, and investigate the associated factors. METHODS: Data were collected retrospectively from 47 subjects (94 eyes) and the peripheral leakage results based on fluorescein angiography were analyzed. The relationship between peripheral leakage findings and other factors including-arm-retinal circulation time (ARCT) and venous filling time (VFT), refractive error, age, hypertension, and diabetes- was evaluated. RESULTS: Ten eyes had peripheral leakage (21.3%). The mean age was 34.7 +/- 7.86 years in the non-leakage group and 44.3 +/- 9.63 years in the leakage group; the difference between the groups was statistically significant (p = 0.001). The mean spherical equivalent was -2.85 +/- 2.71 diopter in the non-leakage group and -3.46 +/- 3.62 diopter in the leakage group; the difference between the groups were not significant (p = 0.471). The mean ARCT was 10.50 +/- 2.06 seconds in the non-leakage group and 11.76 +/- 2.47 seconds in the leakage group; the difference between the groups was statistically significant (p = 0.041). The mean VFT was 9.70 +/- 1.91 seconds in the non-leakage group and 10.75 +/- 1.40 seconds in the leakage group; the difference between the groups was statistically significant (p = 0.048). CONCLUSIONS: Peripheral leakage can be found in asymptomatic eyes. Age, VFT, and ARCT were correlated to peripheral leakage findings based on angiography. These leakage findings were thought to be related with histological properties and physiological changes in peripheral retina.
Key Words: Arm-retinal circulation time;Fluorescein angiography;Peripheral leakage;Venous filling time


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