J Korean Ophthalmol Soc > Volume 60(5); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(5):474-479.
DOI: https://doi.org/10.3341/jkos.2019.60.5.474    Published online May 15, 2019.
Polymicrobial Keratitis of Pseudomonas aeruginosa, Acinetobacter baumannii, and Ochrobactrum anthropi.
Jung Youb Kang, Ju Hwan Song, Ki Yup Nam, Seung Uk Lee, Sang Joon Lee
1BGN Eye Clinic, Busan, Korea.
2The Bom Eye Clinic, Busan, Korea.
3Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Changwon, Korea.
4Department of Ophthalmology, Kosin University College of Medicine, Busan, Korea. hhiatus@gmail.com
5Institute for Medicine, Kosin University College of Medicine, Busan, Korea.
녹농균, 아시네토박토 바우마니, 오크로박트럼 안트로피 복합감염에 의한 각막염
강정엽1⋅송주환2⋅남기엽3⋅이승욱4⋅이상준4,5
BGN 밝은눈안과1, 명지더봄안과2, 창원경상대학교병원 안과3, 고신대학교 의과대학 안과학교실4, 고신대학교 의과학연구소5
Correspondence:  Sang Joon Lee,
Email: hhiatus@gmail.com
Received: 12 July 2018   • Revised: 27 August 2018   • Accepted: 23 April 2019
Abstract
PURPOSE
To report polymicrobial keratitis involving Pseudomonas aeruginosa, Acinetobacter baumannii, and Ochrobactrum anthropi. CASE SUMMARY: A 53-year-old female complained of pain and secretion in her right eye, which started 6 weeks before her visit. She applied steroid ointment, which was received from the dermatologist, to her eyelid 7 days prior to her visit but this treatment worsened her symptoms. At the initial visit, the visual acuity of the right eye was light perception, and purulent secretions were observed. Using a slit lamp, severe conjunctival hyperemia, hypopyon, and a ring-shaped central corneal ulcer were observed. The anterior chamber and fundus were not observed due to corneal lesions but ultrasonography showed no intraocular inflammation. Infectious keratitis was suspected and cultured by corneal scraping. During the incubation period, 0.5% moxifloxacin, 2% voriconazole, and 1% cyclopentolate were administered. A total of 400 mg of moxifloxacin and 100 mg of doxycycline were given orally. In the primary culture, Pseudomonas aeruginosa and Acinetobacter baumannii were identified so 5% ceftazidime, which was sensitive for the antibiotic susceptibility results was further instilled. Thereafter, the keratitis improved but the keratitis again worsened while maintaining the topical treatment. A secondary culture was positive for Ochrobactrum anthropi. Treatment with 1.4% gentamicin, which was sensitive for the antibiotic susceptibility test was added and the keratitis improved. A conjunctival flap was performed because of the increased risk of perforation. CONCLUSIONS: We report polymicrobial keratitis involving Pseudomonas aeruginosa, Acinetobacter baumannii, and Ochrobactrum anthropi for the first time in the Republic of Korea.
Key Words: Acinetobacter baumannii;Keratitis;Ochrobactrum anthropi;Pseudomonas aeruginosa


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