J Korean Ophthalmol Soc > Volume 60(11); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(11):1112-1116.
DOI: https://doi.org/10.3341/jkos.2019.60.11.1112    Published online November 15, 2019.
Infectious Crystalline Keratopathy Caused by Alternaria.
Hye Jin Hong, Jong Myoung Yun, Dae Jin Park
Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea. dj_oph_2540@hanmail.net
<i>Alternaria</i>에 의한 감염결정각막병증
홍혜진 · 윤종명 · 박대진
대구파티마병원 안과
Correspondence:  Dae Jin Park,
Email: dj_oph_2540@hanmail.net
Received: 7 June 2019   • Revised: 4 July 2019   • Accepted: 23 October 2019
Abstract
PURPOSE
To report a case of infectious crystalline keratopathy caused by Alternaria in the corneal center. CASE SUMMARY: A 66-year-old male visited our clinic with right ocular pain and visual loss after corneal trauma caused by a foreign body hitting his right eye while performing farm work 1 month prior to his visit. The patient had no history of corneal surgery and long-term use of topical corticosteroid. A corneal epithelial defect and whitish snowflake margin infiltration around the corneal stroma were observed in the corneal center, but there was an absence of conjunctival injection and anterior segment inflammation. Cultures and a biopsy of the corneal scrapings revealed Alternaria species fungus. The patient was treated with 1% topical voriconazole and 0.5% moxifloxacin, together with oral voriconazole (400 mg/day). After 2 months of treatment, the disease was completely cured, with a minute corneal opacity. CONCLUSIONS: We successfully treated a rare case of infectious crystalline keratopathy caused by Alternaria, which has not been previously reported in the Republic of Korea.
Key Words: Alternaria spp.;Corneal trauma;Infectious crystalline keratopathy


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