| Systemic Lupus Erythematosus Presenting as Monocular Elevation Deficiency. |
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Seung Woo Kim, Yong Hyun Kim, Seung Ah Chung |
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Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea. mingming8@naver.com |
| 한 눈 상전장애로 나타난 전신홍반루푸스 1예 |
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김승우⋅김용현⋅정승아 |
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아주대학교 의과대학 안과학교실 |
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| Abstract |
PURPOSE
To report a case of monocular elevation deficiency as the presenting manifestation of systemic lupus erythematosus (SLE). CASE SUMMARY: A 23-year-old, otherwise healthy female presented with a 3-day history of vertical diplopia and headache. She had a left hypotropia, which worsened in adduction and supra-duction and a profound inferior oblique underaction (-3). Magnetic resonance imaging showed an enhancement around the left superior oblique muscle and multiple infarctions in the left midbrain. On repetitive serological tests, anemia, lymphopenia, and anti-phospholipid antibody were positive. A presumptive diagnosis was a myositis of left superior oblique muscle and hyper-coagulation related with anti-phospholipid antibody. Two months after high-dose steroid treatment, the vertical diplopia was resolved. Five months later, the left hypotropia recurred as a more severe form with the inability to elevate the left eye in all directions. In addition, the infarction associated with vasculitis recurred in the left midbrain. As the treatment with high-dose steroid failed to relieve her ocular symptoms, recession of the left inferior rectus was performed 8 months later. One month after the surgery, she developed multiple lesions of erythematous nodosa with tenderness. Skin biopsy of the lesion in the fingers showed the histological findings consistent with lupus. CONCLUSIONS: Eye movement abnormality can be an initial manifestation of SLE, which should be considered as a differential diagnosis especially in young female patients. |
| Key Words:
Anti-phospholipid antibody;Monocular elevation deficiency;Systemic lupus erythematosus |
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