J Korean Ophthalmol Soc > Volume 56(7); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(7):1065-1074.
DOI: https://doi.org/10.3341/jkos.2015.56.7.1065    Published online July 15, 2015.
Analysis of Choroidal Thickness Measured Using RTVue and Associated Factors in Open-Angle Glaucoma.
Sang Wook Jin, Woo Seok Choi, Hong Ryung Seo, Seung Soo Rho, Sae Heun Rho
1Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea. shrho@dau.ac.kr
2Department of Ophthalmology, Wallace Memorial Baptist Hospital, Busan, Korea.
3Department of Ophthalmology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
RTVue 빛간섭단층촬영기로 측정한 맥락막 두께와 연관인자에 관한 연구
진상욱1⋅최우석1⋅서홍융2⋅노승수3⋅노세현1
동아대학교 의과대학 안과학교실1, 왈레스기념 침례병원 안과2, 차의과대학교 의학전문대학원 분당차병원 안과학교실3
Received: 28 November 2014   • Revised: 16 February 2015   • Accepted: 4 June 2015
Abstract
PURPOSE
To compare the macular choroidal thickness, ganglion cell complex thickness, peripapillary choroidal thickness and retinal nerve fiber layer thickness among normal, primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) patients using RTVue (Fourier-domain optical coherence tomography; Optovue, Fremont, CA, USA). METHODS: A retrospective analysis of 32 normal controls, 32 POAG and 52 NTG patients was performed. Choroidal thickness, ganglion cell complex thickness and retinal nerve fiber layer thickness were compared among normal controls, POAG and NTG subjects. Additionally, the factors influencing choroidal thickness (age, axial length, spherical equivalent, central corneal thickness, mean deviation, nocturnal dip, blood pressure variability) were analyzed. RESULTS: A total of 32 normal controls, 32 POAG and 52 NTG patients were enrolled in this study. Macular and peripapillary choroidal thicknesses were significantly thinner in the NTG patients. In NTG subjects, the significant influencing factors associated with macular and peripapillary choroidal thicknesses were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant influencing factors associated with macular and peripapillary choroidal thicknesses were age and axial length. CONCLUSIONS: Choroidal thickness was significantly thinner in NTG patients compared with normal controls and POAG patients. Factors influencing choroidal thickness in NTG patients were age, axial length, nocturnal dip (diastolic blood pressure), diastolic blood pressure variability and ganglion cell complex thickness. In POAG patients, significant factors influencing choroidal thickness were age and axial length.
Key Words: Blood pressure variability;Choroidal thickness;Nocturnal dip;RTVue


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