| Repeatability of Peripapillary Atrophy Parameters Measured Using Optic Disc Stereophotography and Evaluation of Its Diagnostic Ability. |
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Il Suk Yun, Mar Vin Lee |
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Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea. mvdevil@daum.net |
| 시신경입체사진으로 측정한 시신경유두주위위축 넓이의 재현성과 녹내장안 진단의 유용성 |
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윤일석⋅이마빈 |
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Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea |
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| Abstract |
PURPOSE
To investigate the measurement repeatability of peripapillary atrophy (PPA) parameters obtained by optic disc stereophotography (ODP) and evaluate the usefulness of PPA parameters to differentiate open-angle glaucoma (OAG) from normal eyes in patients with PPA. METHODS: Sixty-five eyes of 65 patients with PPA were examined. Disc area, cup area, rim area, vertical cup to disc (CD) ratio, CD area ratio, PPA area, zone beta (beta) area and zone alpha (alpha) area were obtained by ODP using intrinsic algorithms. The area under the receivers operating characteristic (AUROC) curves was used to compare the PPA parameters with that of the disc parameters to differentiate OAG from normal eyes. Two examiners analyzed PPA parameters to confirm reproducibility and repeatability of ODP. RESULTS: Vertical CD ratio (VCD), area CD ratio, zone beta area, zone beta area per PPA area, zone beta area per disc area and axial length were significantly larger in OAG patients (p < 0.05). Among PPA parameters, zone beta area per PPA area was strongly correlated with MD (r =-0.431) and PSD (r = 0.411). In addition, PPA (area) to disc area ratio showed the best diagnostic ability (AUROC curve value of 0.786) when comparing the OAG group to the normal group. PPA area and zone beta area obtained by ODP showed good reproducibility and repeatability (ICC > 0.997). CONCLUSIONS: The PPA measurement obtained by ODP has good reproducibility and consistency and can be a useful tool in monitoring PPA changes in glaucoma patients. |
| Key Words:
Glaucoma;Optic disc stereophotography;Peripapillary atrophy;Reproducibility;Zone beta |
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