J Korean Ophthalmol Soc > Volume 55(3); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(3):443-448.
DOI: https://doi.org/10.3341/jkos.2014.55.3.443    Published online March 15, 2014.
Two Cases of Superior Limbic Keratoconjunctivitis Treated with Bevacizumab and Triamcinolone Injection.
Won Soo Kim, Sung Wook Wee, Jae Chan Kim
Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Korea. jck50ey@kornet.net
상윤부 각결막염 환자에서 베바시주맙과 트리암시놀론 주사를 이용해 치료한 증례 2예
김원수⋅위성욱⋅김재찬
Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Korea
Abstract
PURPOSE
To report two cases of intractable superior limbic keratoconjunctivitis (SLK) treated with bevacizumab and triamcinolone injection. CASE SUMMARY: A 69-year-old female visited our clinic with pain in the left eye for 3 days and was diagnosed with SLK in her left eye. After 3 months of using steroid eye drops, artificial tears, and oral steroid intermittently, there was no improvement in symptoms and signs, thus this case was considered intractable with the conventional therapy. A mixture of bevacizumab (0.15 cc) and triamcinolone (0.05 cc) was injected into the sub-tenon's capsule of the left eye. After 1 week, all symptoms and signs disappeared, and there was no recurrence for 6 months. A 55-year-old female was transferred to our clinic due to SLK that did not respond to artificial tears, steroid eye drops, punctal occlusion, and botox injection for 3 months. A mixture of bevacizumab (0.15 cc) and triamcinolone (0.05 cc) was injected into the sub-tenon's capsule of the left eye. After 2 weeks, all symptoms and signs were improved, and there was no recurrence for 4 months. CONCLUSIONS: The presented 2 SLK cases are meaningful, because neovascularization disappeared and controlled inflammation was obtained following sub-tenon injection with both bevacizumab and triamcinolone.
Key Words: Bevacizumab;Superior limbic keratoconjunctivitis;Triamcinolone


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