J Korean Ophthalmol Soc > Volume 54(6); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(6):982-986.
DOI: https://doi.org/10.3341/jkos.2013.54.6.982    Published online June 15, 2013.
A Case of Dexamethasone Intravitreal Implant Fragmentation During the Injection Procedure in Central Retinal Vein Occlusion.
Sang Moon Youn, Sung Jin Park, Ho Young Lee, Sung Hyup Lim, Il Han Yun
1Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. happytriad@gmail.com
2Therapeutics Center for Ocular Neovascular Disease, Busan, Korea.
중심망막정맥폐쇄 환자에서 덱사메타손 유리체강내 삽입물 주입 시 발생한 분절화 1예
윤상문1,2⋅박성진1,2⋅이호영1,2⋅임성협1,2⋅윤일한1
Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine1, Busan, Korea
Therapeutics Center for Ocular Neovascular Disease2, Busan, Korea
Abstract
PURPOSE
We report a case of dexamethasone intravitreal implant (Ozurdex(R); Allergan, Inc.) fragmentation during the injection procedure in macular edema due to central retinal vein occlusion. CASE SUMMARY: A 57-year-old man visited our hospital for visual disturbance in his right eye. The patient's best-corrected visual acuity was 0.02 in the right eye and 1.2 in the left eye. After fundus examination, the patient was diagnosed with central retinal vein occlusion with macular edema, thus bevacizumab was injected in the right eye. However, the macular edema did not improve, and a dexamethasone intravitreal implant was injected in the right eye. Immediately after the dexamethasone intravitreal implant injection, on fundus exam, the drug was observed to be fragmented into 3 pieces without any additional treatment. After 2 months, the patient's best-corrected visual acuity was 0.4 in the right eye and 1.2 in the left eye. Macular edema decreased according to optical coherence tomography. CONCLUSIONS: A case of dexamethasone intravitreal implant fragmentation during an injection procedure has not been previously reported in Korea. Although the drug fragmented, the treatment was effective without complications.
Key Words: Dexamethasone intravitreal implant;Fragmentation;Ozurdex(R)


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