| Histopathologic Features of Triamcinolone Deposits in Refractory Steroid-Induced Glaucoma after Subtenon Triamcinolone Injection. |
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Hye Shin Jeon, Won Young Park, Ji Woong Lee, Ji Eun Lee, Boo Sup Oum |
1Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea. alertlee@hanmail.net
2Department of Pathology, Pusan National University School of Medicine, Busan, Korea. |
| 테논낭하 트리암시놀론 주입술 후 발생한 난치성 녹내장에서 침적물의 조직병리학적 소견 |
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전혜신1⋅박원영2⋅이지웅1⋅이지은1⋅엄부섭1 |
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Departments of Ophthalmology1, Pathology2, Pusan National University School of Medicine, Busan, Korea |
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| Abstract |
PURPOSE
To report the removal of subtenon triamcinolone precipitates in patients with refractory steroid-induced glaucoma following subtenon triamcinolone injection. CASE SUMMARY: A 72-year-old male patient with diabetic retinopathy had cystoid macular edema in the right eye. The patient received a posterior subtenon injection of triamcinolone acetonide and developed intractable glaucoma one month after the injection in the right eye. Corticosteroid-deposit was excised three month after the injection. The intraocular pressure decreased to normal within one month after surgery and remained normal for seven months after surgery. A 42-year-old man with bilateral chronic recurrent anterior uveitis received a posterior subtenon triamcinolone acetonide injection in both eyes. The patient developed refractory steroid-induced glaucoma one month after the injection in the right eye. Corticosteroid-deposit was excised six months after the injection in the right eye. The patient's intraocular pressure decreased to normal within two weeks after surgery and remained normal. Light microscopy showed a fibrous capsule encapsulating an amorphous whitish material. The excised specimen with polarized light showed birefringence of triamcinolone crystals within an encapsulated cyst. CONCLUSIONS: Removal of subtenon triamcinolone acetonide precipitate may facilitate the management of patients developing increased intraocular pressure unresponsive to maximum tolerable medical therapy and should be considered before performing glaucoma filtration surgery. |
| Key Words:
Glaucoma;Subtenon;Triamcinolone |
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