A Case of Primary Eyelid Peripheral T-Cell Lymphoma, Not Otherwise Specified.

Noh, Si Jin; Kie, Jeong Hae; Kim, Hye Young

doi:2012.53.11.1685

J Korean Ophthalmol Soc > Volume 53(11); 2012 > Article

Case Report

Journal of the Korean Ophthalmological Society 2012;53(11):1685-1688.
DOI: https://doi.org/10.3341/jkos.2012.53.11.1685 Published online November 15, 2012.

A Case of Primary Eyelid Peripheral T-Cell Lymphoma, Not Otherwise Specified.

Si Jin Noh, Jeong Hae Kie, Hye Young Kim

¹Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
²Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
³Department of Ophthalmology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea. khyeye@paran.com

위눈꺼풀에 발생한 원발성 기타 상세불명의 말초 T세포 림프종 1예

노시진¹⋅기정혜²⋅김혜영³

Department of Ophthalmology, Yonsei University College of Medicine¹, Seoul, Korea
Departments of Pathology² and Ophthalmology³, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea

Abstract

PURPOSE
To report a case of primary peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), of the eyelid. METHODS: A 48-year-old healthy male patient presented with a mass on the upper lid of 2 months in duration. The lesion was reddish, well-demarcated, oval shaped, and measured approximately 8 x 4 mm. The mass did not respond to incisional drainage and intra-lesional triamcinolone. An excisional biopsy for diagnosis was performed. RESULTS: On microscopic examination, a localized dense lymphocytic infiltration was observed in the subepithelial area, and cytologic atypia was observed under high power. On immunohistochemical examination, tumor cells were positive for CD3 but negative for CD20, CD30, CD56, k-light chain immunoglobulin, lambda-light chain immunoglobulin, and increased Ki-67 activity was noted. A histopathological diagnosis of PTCL-NOS was made. CONCLUSIONS: PTCL-NOS, which rarely occurs on the eyelids, commonly accompanies generalized lymphadenopathy and "B symptoms" such as fever and weight loss. Herein, the authors report a case of PTCL-NOS of the eyelid presenting as a rapidly growing solid mass in an otherwise healthy patient.

Key Words: Eyelid tumor;Peripheral T-cell lymphoma;not otherwise specified