Macular Thickness Changes with Age and Gender in Emmetropia Using Spectral Domain Optical Coherence Tomography.

Kim, Seung Hoon; Choi, Kyung Seek; Lee, Sung Jin

doi:2011.52.3.299

J Korean Ophthalmol Soc > Volume 52(3); 2011 > Article

Original Article

Journal of the Korean Ophthalmological Society 2011;52(3):299-307.
DOI: https://doi.org/10.3341/jkos.2011.52.3.299 Published online March 15, 2011.

Macular Thickness Changes with Age and Gender in Emmetropia Using Spectral Domain Optical Coherence Tomography.

Seung Hoon Kim, Kyung Seek Choi, Sung Jin Lee

Department of Ophthalmology, College of Medicine, Soonchunhyang University, Seoul, Korea. wismile@unitel.co.kr

정시안에서 스펙트럼영역 빛간섭단층촬영기를 이용한 연령과 성별에 따른 황반 두께의 변화

김승훈⋅최경식⋅이성진

Department of Ophthalmology, College of Medicine, Soonchunhyang University, Seoul, Korea

Abstract

PURPOSE
To evaluate the changes in macular thickness with regard to age and gender in normal subjects with emmetropia using spectral domain optical coherence tomography. METHODS: The present study consisted of 90 healthy subjects (162 eyes) with no ophthalmic evidence of retinopathy and who had emmetropic eyes. The data from macular measurements using spectral domain optical coherence tomography was analyzed according to the groups divided by age (Group 1: 0 to 19 years of age, Group 2: 20 to 39 years of age, Group 3: 40 to 59 years of age, Group 4: 60 to 80 years of age) and gender. RESULTS: Macular thickness of the central circle was 253.40 +/- 23.03 microm in all subjects. There was no significant change with age (p > 0.05). However, the measurements at the inner (3 mm) and outer circle (6 mm) showed a reduction of macular thickness with age (p < 0.05). The macular thickness at the central and inner circle was significantly lower in the female subjects (p < 0.05). In group 3 and 4, macular thickness at the central circle in males was greater than in females. In group 3, the average inner macular thickness in males was significantly greater than in females (p < 0.05). CONCLUSIONS: In normal subjects with emmetropia, there are statistically significant differences in macular thickness between subjects of different age and gender. The results from the present study can be expected to provide a reference value for evaluating macular disease.

Key Words: Age;Emmetropia;Gender;Macular thickness;Spectral domain optical coherence tomography