J Korean Ophthalmol Soc > Volume 51(5); 2010 > Article
Journal of the Korean Ophthalmological Society 2010;51(5):764-768.
DOI: https://doi.org/10.3341/jkos.2010.51.5.764    Published online May 15, 2010.
Surgical Treatment of Extensive Conjunctival Melanocytic Nevus Mimicking Conjunctival Melanoma.
Dong Hyun Jo, Min Joung Lee, Young Keun Han, Ji Won Kwon
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. eyeminerva@yahoo.co.kr
2Department of Ophthalmology, Seoul National University Hospital Boramae Hospital, Seoul, Korea.
3Seoul National University Hospital, Health Care System Gangnam Center, Healthcare Research Institute, Seoul, Korea.
결막 흑색종의 양상을 보인 광범위 결막 모반의 수술적 치료
조동현1ㆍ이민정1ㆍ한영근2ㆍ권지원1,3
Department of Ophthalmology, Seoul National University College of Medicine, Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute1, Seoul, Korea Department of Ophthalmology, Seoul National University Hospital Boramae Hospital2, Seoul, Korea Seoul National University Hospital, Health Care System Gangnam Center, Healthcare Research Institute3, Seoul, Korea
Abstract
PURPOSE
To report a case of diffuse conjunctival melanocytic lesion mimicking conjunctival melanoma and treated by surgical excision and amniotic membrane transplantation. CASE SUMMARY: A 29-year-old man presented with diffuse pigmented lesion on the bulbar conjunctiva in the right eye, which had been present since birth. Circumferential pigmentation was observed in the perilimbal conjunctiva from 4 to 11 o'clock, and slightly elevated, dark brown-colored lesions with multiple small cysts were noted on the superior, inferior, and temporal bulbar conjunctiva. Incisional biopsy was performed from multiple sites to rule out conjunctival melanoma. Histopathologic examination showed small nevus cells and multiple cysts. Under local anesthesia, temporal conjunctival excision and amniotic membrane transplantation were performed. The surgical pathologist confirmed compound nevus. Four weeks after the surgery, full epithelialization was observed over the amniotic membrane. Several lesions were intentionally left during the surgery, and unnoticeable from the frontal view. The patient was satisfied with the surgical result. CONCLUSIONS: In extensive conjunctival pigmented lesion, biopsy should always be performed to rule out melanoma. Temporal conjunctival excision rather than whole lesion excision can be a cosmetically good surgical option for a diffuse conjuntival lesion proven as a benign conjunctival nevus.
Key Words: Malignant melanoma;Melanocytic nevus


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