J Korean Ophthalmol Soc > Volume 49(9); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(9):1525-1531.
DOI: https://doi.org/10.3341/jkos.2008.49.9.1525    Published online September 15, 2008.
Corneal Opacity Caused by LASEK with Improper High-concentrated Mitomycin-C.
Su Jin Kim, Min Ho Lee, Eun Hee Kim, Jong Soo Lee
1Department of ophthalmology, College of Medicine, Pusan National University, Pusan, Korea. Jongsool@pusan.ac.kr
2Department of ophthalmology, College of Medicine, Pusan St. Mary's Medical Center, Pusan, Korea.
라섹 술중 잘못 사용된 고농도 마이토마이신 C에 의한 각막혼탁
김수진1ㆍ이민호1ㆍ김은희2ㆍ이종수1
Department of ophthalmology, College of Medicine, Pusan National University1, Pusan, Korea / Pusan St. Mary’s Medical Center2, Pusan, Korea
Abstract
PURPOSE
To report a case of corneal opacity with postoperative changes of topographic features and visual acuity after laser subepithelial keratomileusis (LASEK) treated with an improper concentration of mitomycin-C. CASE SUMMARY: A 25-year-old female patient who experienced corneal opacity after LASEK treated with mitomycin-C was evaluated for changes in corneal opacity by photography, central corneal power by Orb scan uz, and best corrected visual acuity (BCVA) over the period of 1 year. The corneal epithelial defect was completely healed 2 weeks after the LASEK operation. Subepithelial and stromal opacity decreased over time, but her cornea did not return to normal. BCVA was 20/25 in the right eye and 20/20 in the left eye at postoperative 1 year, but stromal opacity remained. CONCLUSIONS: An improper concentration of mitomycin-C during LASEK could result in corneal opacity. Long time is needed to recover visual acuity and a normal corneal structure.
Key Words: Corneal opacity;LASEK;Mitomycin-C
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