Two Cases of Conjunctival Mucosa-associated Lymphoid Tissue (MALT) Lymphomas Treated by Cryotherapy.

Chang, Woo Seok; Park, Jae Bok; Kim, Keun Hae; Kim, Sook Young

doi:2008.49.7.1165

J Korean Ophthalmol Soc > Volume 49(7); 2008 > Article

Case Report

Journal of the Korean Ophthalmological Society 2008;49(7):1165-1172.
DOI: https://doi.org/10.3341/jkos.2008.49.7.1165 Published online July 15, 2008.

Two Cases of Conjunctival Mucosa-associated Lymphoid Tissue (MALT) Lymphomas Treated by Cryotherapy.

Woo Seok Chang, Jae Bok Park, Keun Hae Kim, Sook Young Kim

¹Department of Ophthalmology, College of Medicine, Catholic University of Daegu, Daegu, Korea. kimkh@cu.ac.kr
²Department of Pathology, College of Medicine, Catholic University of Daegu, Daegu, Korea.

결막에 국한된 점막연관 림프조직형 림프종에서 냉동요법을 이용한 치료 2예

장우석¹ㆍ박재복²ㆍ김숙영¹ㆍ김근해¹

Department of Ophthalmology, College of Medicine, Catholic University of Daegu1, Daegu, Korea, Department of Pathology, College of Medicine, Catholic University of Daegu2, Daegu, Korea

Correspondence: Woo-Seok Chang, M.D.1

Abstract

PURPOSE
To report two cases of conjunctival mucosa-associated lymphoid tissue (MALT) lymphomas treated with cryotherapy. CASE SUMMARY: Two patients with MALT lymphoma of the conjunctiva were treated by carbon dioxide cryotherapy under topical anesthesia using 0.5% proparacaine hydrochloride (Alcaine(R), Alcon). Cryotherapy was repeated in recurrent lesions up to three times. One patient was free of the tumor for 18 months of follow-up after the third cryotherapy was performed. The second patient had complete disease arrest for 9 months after the third cryotherapy. Neither patient experienced complications during the follow-up period. CONCLUSIONS: Cryotherapy is a comparatively easy treatment tool with fewer complications for patients, making it preferable from a patient's perspective as well. Cryotherapy may be a useful treatment modality in patients with MALT lymphomas localized to the conjunctiva.

Key Words: Conjunctiva;Cryotherapy;MALT lymphoma