| The Epidemiologic and Clinical Characteristics of Thyroid-Associated Orbitopathy. |
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Dong Ah Ko, Byoung Jin Kim, Michael Kazim |
1Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University, College of Medicine, Seoul, Korea. feeloph@naver.com
2Department of Ophthalmology, New York Presbyterian Hospital, Columbia University, College of Physicians and Surgeons, New York, U.S.A. |
| 갑상샘연관안와병증의 역학과 임상양상 |
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고동아1,김병진1,Michael Kazim2 |
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Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University,, College of Medicine1, Seoul, Korea Department of Ophthalmology, New York Presbyterian Hospital, Columbia University, College of Physicians and Surgeons2, New York, U.S.A. |
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Correspondence:
Dong Ah Ko, M.D.1 |
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| Abstract |
PURPOSE
To determine the epidemiologic and clinical characteristics of thyroid-associated orbitopathy (TAO). METHODS: We retrospectively studied the clinical data of 385 patients from the New York City area diagnosed with TAO from January 1990 to December 2000. The total cases were divided into male and female groups and age-adjusted relative incidence rates were obtained to plot the incidence curve and clinical characteristics. Statistical analysis was applied to the collected data. RESULTS: The average age of patients with TAO was 46.3 years for females and 50.1 years for males. The female-male ratio was 5.31:1. In 23.3% of patients, the diagnosis of TAO was made simultaneously with their thyroid disease. In 75% of cases, the diagnosis was made within 18 months of the presentation of thyroid disease. Soft tissue involvement was noted most frequently in 311 (80.8%), eyelid retraction in 306 (79.5%), proptosis in 278 (72.2%), restrictive myopathy in 234 (60.8%), and compressive optic neuropathy in 43 (11.2%) of 385 patients. CONCLUSIONS: TAO has variable and different epidemiologic and clinical characteristics according to sex and age. |
| Key Words:
Thyroid-associated orbitopathy (TAO);Thyroid ophthalmopathy;Epidemiology;Clinical characteristics |
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