| Short-term Change in Corneal Endothelium after Iris-Fixed Phakic Intraocular Lens Insertion. |
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Eun Suk Lee, Young Jae Cho, Eung Kweon Kim |
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The Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea. eungkkim@yumc.yonsei.ac.kr |
| 홍채고정 유수정체용 인공수정체 삽입술 시행 후 각막 내피세포의 단기 변화 |
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이은석,조영재,김응권 |
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The Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea |
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Correspondence:
Eun-Suk Lee, M.D. |
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| Abstract |
PURPOSE
To investigate endothelial change in phakic eyes implanted with Artisan phakic IOL inserts and to identify the associated factors. METHODS: We prospectively examined the endothelial change in 11 phakic eyes implanted with Artisan phakic IOL inserts. Noncontact specular microscopy was performed preoperatively, and at 1 week and 1 month postoperatively. RESULTS: The mean endothelial cell loss was 3.57% at 1 week, and 4.69% at 1 month. There was a statistically significant decrease in endothelial cell density and an increase in pleomorphism and polymegathism of the cells after the surgery which indicate cellular damage (p<0.05). There were no statistically significant changes in endothelial cell density, shape, or size between 1 week and 1 month postoperatively (p>0.05). No correlation was observed between cell loss and corneal curvature, critical distance, IOL optic size, IOL diopter, or serial order of the operation. However, there was significant negative correlation (R=-7.600; p>0.05) between cell loss and anterior chamber depth. CONCLUSIONS: Endothelial damage occurred primarily during the surgical procedure and special attention should be given to patients with shallow anterior chamber depth for iris-fixed phakic IOL inserts to avoid unintended endothelial damage. |
| Key Words:
Corneal endothelial cell;Iris-fixed phakic intraocular lens;Myopia |
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