The Clinical Usefulness of the Venous Filling Time in Proliferative Diabetic Retinopathy. |
Seong Soo Jang, Yun Sik Yang |
Department of Ophthalmology, Wonkwang University College of Medicine, Iksan, Cheonbuk, Korea. ysyang@wonkwang.ac.kr |
증식당뇨망막병증에서 망막정맥충만시간의 임상적 유용성 |
장성수 ( Seong Soo Jang ) , 양연식 ( Yun Sik Yang ) |
|
|
Abstract |
PURPOSE To evaluate the clinical usefulness of venous filling time (VFT) in proliferative diabetic retinopathy (PDR) and the relation of VFT with PDR complications. METHODS: Retinal circulation time (RCT) such as ART (arm to retinal circulation time), AVP (arteriovenous passage time), and VFT (venous filling time) were obtained by video fluorescein angiogram using SLO (Scanning Laser Ophthalmoscope), after which PRP (panretinal photocoagulation) was performed. We performed two studies on 39 patients, (39 eyes), who had PDR. In the first study, according to the development of complication, patients were classified into 2 groups, stabilized and complicated groups. In the second study, according to the score of the risk factor by DRS (Diabetic Retinopathy Study), patients were classified into 4 groups, A (1 score), B (2 score), C (3 score), and D (4 score) groups. RCTs, especially VFT were analyzed with each group. RESULTS: In the Mann-Whitney test, the Z-values of ART, AVP and VFT were -1.92, -0.49, and -2.59, respectively. There was a significant difference only in VFT(P<0.05). According to the risk factor scores, VFTs were 7.48 +/- 1.36, 7.84 +/- 0.91, 9.15 +/- 1.10, and 10.94 +/- 0.44 sec in A, B, C, and D groups, respectively. In each group, there were significant differences, except between A and B. CONCLUSIONS: VFT was delayed in the complicated group. With increasing risk factor score, VFT was more delayed. We suggest that VFT is a predictable indicator of the progression and development of complication in PDR. |
Key Words:
Proliferative diabetic retinopathy;Risk factor;Venous filling time |
|