Phototherapeutic Keratectomy of Avellino Corneal Dystrophy with 0.02% Mitomycin C.

Chae, Ju Byung; Kim, Tae Im; Tchah, Hungwon

Original Article

Journal of the Korean Ophthalmological Society 2003;44(12):2742-2746.
Published online December 1, 2003.

Phototherapeutic Keratectomy of Avellino Corneal Dystrophy with 0.02% Mitomycin C.

Ju Byung Chae, Tae Im Kim, Hungwon Tchah

Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Korea. hwtchah@amc.seoul.kr

Avellino 각막이영양증 환자에서 Mitomycin C 0.02%를 이용한 치료적 엑시머레이저 각막절제술 2예

채주병 ( Chae Ju Byeong ) , 김태임 ( Kim Tae Im ) , 차흥원 ( Cha Heung Won )

Abstract

PURPOSE
We report two cases of phototherapeutic keratectomy(PTK) treatment of Avellino corneal dystrophy with topical intraoperative application of 0.02% mitomycin C(MMC). METHODS: In the first case, a 27-year-old woman who had recurrent Avellino corneal dystrophy after uncomplicated bilateral LASIK underwent PTK, and then intraoperative 0.02% MMC applied topically with a soaked microsponge at the posterior corneal flap surface and the stromal bed and vigorous irrigation. In the second case, a 30-year-old man who had recurrent Avellino corneal dystrophy despite seven PTKs, underwent PTK with intraoperative 0.02% MMC at the corneal surface. RESULTS: In the first case, the preoperative best corrected visual acuity(BCVA) was 20/200. And 9 months after the operation, uncorrected visual acuity was 20/25. In the second case, the preoperative BCVA was 20/200. And 6 months of follow-up, BCVA was 20/25 and there was no evidence of recurrence. CONCLUSIONS: The intraoperative use of topical 0.02% MMC in conjunction with PTK may prevent or delay the recurrence of Avellino corneal dystrophy.

Key Words: Avellino corneal dystrophy;Mitomycin C;Phototherapeutic keratectomy