Bilateral Acute Retinal Necrosis Syndrome in the Patient with Acquired Immunodeficiency Syndrome.

Kim, Sang Jin; Yu, Hyeong Gon

Case Report

Journal of the Korean Ophthalmological Society 2003;44(10):2445-2450.
Published online October 1, 2003.

Bilateral Acute Retinal Necrosis Syndrome in the Patient with Acquired Immunodeficiency Syndrome.

¹Department of Ophthalmology, Seoul National University College of Medicine, Korea.
²Seoul Artificial Eye Center Seoul National University Hospital Clinical Research Institute, Korea. hgonyu@snu.ac.kr

후천성면역결핍증후군 환자에서 발생한 양안 급성망막괴사증후군 1예

김상진 ( Kim Sang Jin ) , 유형곤 ( Yu Hyeong Gon )

Abstract

PURPOSE
To report one case of bilateral acute retinal necrosis (ARN) syndrome in the patient with acquired immunodeficiency syndrome (AIDS). METHODS: Bilateral retinal necrosis, occlusive vasculitis, vitreous opacity and inflammatory reaction in anterior chamber were noted in a 48-years old man with AIDS. RESULTS: The patient was diagnosed as bilateral ARN, but did not respond to intravenous acyclovir therapy. However, the patient was successfully treated with intravenous ganciclovir at a dosage of 5 mg/kg/day, which resulted in resolution of retinal lesion and improvement of visual acuity without complications such as retinal detachment. CONCLUSIONS: CMV retinitis, progressive outer retinal necrosis, ocular syphilis should be considered in the differential diagnosis of ARN syndrome in the AIDS patients and alternative treatment with ganciclovir should be considered promptly when the patient do not respond to acyclovir therapy.

Key Words: Acute retinal necrosis (ARN);AIDS;Ganciclovir