| An Automatic System for the Delivery of Eye-Drops Using a Microinfusion Pump. |
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Ji Won Kwon, Jung Suk Kim, Soo Bong Choi, Jin Hak Lee, Won Ryang Wee |
1Department of Ophthalmology, Seoul National University, College of Medicine, Korea. wrwee@snu.ac.kr
2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Korea.
3Department of Internal Medicine, College of Medicine, Konkuk University, Korea. |
| 마이크로주입펌프를 이용한 자동화된 약물지속방출시스템 |
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권지원 ( Kwon Ji Won ) , 김정숙 ( Kim Jeong Sug ) , 최수봉 ( Choe Su Bong ) , 이진학 ( Lee Jin Hag ) , 위원량 ( Wi Won Lyang ) |
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| Abstract |
PURPOSE
To evaluate the efficacy of continuous drug delivery system using microinfusion pump by animal study METHODS: Schirmer test was performed after connecting the microinfusion pump at the superior fornix of rabbit eye. The pump was settled to instill artificial tears. We also evaluated the efficacy of continuous 0.1% fluorometholone infusion after alkali burn induced by 1N NaOH. RESULTS: Average change in Schirmer tear test value was 12.0mm/5min. The recovery after alkali burn was improved in the eye of continuous infusion of steroid eye drops. CONCLUSIONS: Microinfusion pump was thought to be useful as a continuous eye drops delivery system. It would be applicable to infuse artificial tears continuously in severe dry eye patients and to infuse antibiotic eye drops in infectous eye disease patients. |
| Key Words:
Continuous eye drops delivery system;Microinfusion pump |
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