Measurements of the Diameter and Area of the OpticDisc in Enucleated Human eyes.

Lee, Sung Min; Ko, Myung Kyoo; Choe, Joon Kiu

Original Article

Journal of the Korean Ophthalmological Society 1997;38(1):111-115.
Published online January 1, 1997.

Measurements of the Diameter and Area of the OpticDisc in Enucleated Human eyes.

Sung Min Lee, Myung Kyoo Ko, Joon Kiu Choe

Department of Ophthalmolgy, Collge of Medicine, Hanyang University, Seoul, Korea.

적출안에서의 시신경유두 직경 및 면적측정

이성민(Sung Min Lee),고명규(Myung Kyoo Ko),최준규(Joon Kiu Choe)

Abstract

To measure the optic disc diamete and area in enucleated human eyes, thirty-three enucleated human eyes (20 men, 13 women), with a mean age of 44.2+/-17.7 years (+/-standard deviation; range 8 -74 years), were studied. After enucleation, the globes were immediately fixed in a solution of 10% formalin, were bisected through the optic nerve head and specimens were stained with hematoxylin-eosin. The slides were histomorphometerically evaluated with a light microscope. Each disc was measureed vertically and horizontally on a macrophotograph of the whole specimens with an aligned micromete scale. For correction preparation-induced shrinkage factor, one specimen was measured on the unfixed state. Compared to values obtained in unfixed specimens, preparation-induced shrinkage factor was 6.5% Mean maximal and minimal diameters of the optic disc were 2.16+/-0.15mm (range 1.38 -3.25mm) and 1.79+/-0.44mm (range 1.06 -2.90mm), rrespectively. Mean area of the optic disc was 3.20+/-1.58mm2(range 1.15 - 7.40mm2). These practical values of the optic disc diameter and area may be the important standard units to the further quantiative optic nerve studies.

Key Words: Enucleated human eye;Glaucoma;Ophtic disc;Optic disc size