Histopathologic Findings after Experimental Penetrating Keratoplasty using Dacron-Gore-Tex(R) Combined Graft in Rabbits: Treatment of Corneal Perforation using Synthetic Materials. Report II. |
Jong Kyu Lee, Kee Yong Choi, Byung Joo Yoon |
Department of Ophthalmology, National Medical Center, Seoul, Korea. |
가토각막의 실험적 천공후 시행한 Dacron - Gore - Tex(R) 접합이식편의 조직병리학적 소견 - 합성물질을 이용한 각막천공의 치료 제 2 보 - |
이종규(Jong Kyu Lee),최기용(Kee Yong Choi),윤병주(Byung Joo Yoon) |
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Abstract |
The purpose of this study is to evaluate the histopathologic findings after experimental penetrating keratoplasty using Dacron-Gore-Tex(R) combined graft in rabbits and the clinical efficacy of the treatment of corneal perforation using synthetic materials. Type A which used end to end fixation showed better results than that of type B which used intralamellar fixation and, however, complications and instability of graft occured in most eyes of both types. Type C which modified type B and reduced the thickness of intralamellar portion of graft showed relatively good results compared with type A and B, but there was still instability. Leakage from anterior chamber in early postoperative period prior to fiibrovascular invasion into graft was considered as the main cause of instability of graft. Therefore we performed type D which emphasized on preventing leakage, and well-maintained anterior chamber without extrusion of graft, that is, the best result among all 4 types was observed until 6 weeks postoperatively. Although further study is needed, we think that Dacron-Gore-Tex(R) combined graft can be a good substitute for the management of corneal perforation. |
Key Words:
Corneal perforation;Dacron;Fibrovascular invasion;Gore-Tex(R) Lekage |
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