Slit-Lamp Examination of the Experimentally Induced HSV-I Keratitis.

Kim, Dong Cheol; Ko, Myung Kyoo

Original Article

Journal of the Korean Ophthalmological Society 1988;29(2):251-255.
Published online February 1, 1988.

Slit-Lamp Examination of the Experimentally Induced HSV-I Keratitis.

Dong Cheol Kim, Myung Kyoo Ko

Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.

단순포진 바이러스 - 1 실험적 각막염의 세극등 관찰소견

김동철(Dong Cheol Kim),고명규(Myung Kyoo Ko)

Abstract

This study was performed to observe the sequential charge of the morpholcgic characteristics in experimentally induced herpes simplex keratitis. Duration and morphology of corneal lesion following infection of rabbit cornea with the Kos strain of HSV-I were followed by a daily slit-lamp examination. Three types of virus inoculation methods were used such as scratching, deepithelialization, and intrastromal injection. Herpetic corneal lesions appeared 24 hours after inoculation with punctate and dendritic figures. They persisted up to 14 or 15 days. The characteristic finding in punctate herpetic keratitis was grouped, round-shaped, punctate lesion. When scratching method was emplyed, the most remarkable finding was the discontinuity of the lesion occurred along the scratching wound at relatively regular intervals. There was no difference in lesional morphology and duration between three inoculation methods.