The Effect of Diabetes Mellitus on the Amount of Human Cataractous Lens Protein.

Lee, Jae Sun; Lee, Jin Hak

Original Article

Journal of the Korean Ophthalmological Society 1986;27(4):587-590.
Published online January 1, 2001.

The Effect of Diabetes Mellitus on the Amount of Human Cataractous Lens Protein.

Jae Sun Lee, Jin Hak Lee

Department of Ophthalmology, College of Medicine, Seoul National University, Korea.

Abstract

We have quantified human cataractous lens protein in 10 diabetic patients and 10 non-diabetic patients by using a colorimetric method, to investigate the effect of diabetes mellitus on the amount of human cataractous lens prorein. Protein amount of the diabetic lens cortex(1.26 +/- 0.48mg/ml) was significantly smaller than that of the non-diabetic lens cortex(1.83 +/- 0.44mg/ml) (t=3.36, p<0.005). On the other hand, protein amount of the lens nucleus did not reveal a significant difference between the diabetic(3.06 +/- 0.61mg/ml) and the non-diabetic(3.08 +/- 0.96mg/ml) cataract patients.

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