The Role of Electroretinography in Assessing the Progression of Diabetic Retinopathy. |
Su Eun Park, Hae Jung Sun, Hyun Joon Lee, Tae Kwann Park, Young Hoon Ohn |
1Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea. 2Department of Ophthalmology, Soonchunhyang University College of Medicine, Bucheon, Korea. yhohn@schbc.ac.kr |
당뇨망막병증 진행의 평가를 위한 망막전위도의 유용성 |
박수은1ㆍ선해정2ㆍ이현준2ㆍ박태관2ㆍ온영훈2 |
Department of Ophthalmology, Hallym University College of Medicine1, Seoul, Korea Department of Ophthalmology, Soonchunhyang University College of Medicine2, Bucheon, Korea |
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Abstract |
PURPOSE To investigate the clinical significance of electroretinographic (ERG) responses, including the photopic negative response parameter, in assessing the progression of diabetic retinopathy. METHODS: Standard flash ERG was tested on 28 normal controls and 143 patients who were diagnosed with diabetes mellitus. Of those, 97 patients had diabetic retinopathy in different stages. Electroretinography was performed according to the International Society for Clinical Electrophysiology of Vision (ISCEV) standards. Amplitudes and implicit times of ERG responses, including the photopic negative response (PhNR), were compared at different stages of diabetic retinopathy. RESULTS: Amplitudes of oscillatory potentials were significantly reduced in mild NPDR. Cone b-wave amplitude, 30--Hz flicker response, and PhNR were significantly reduced in moderate NPDR. CONCLUSIONS: These results suggest that oscillatory potentials are good indicators of retinal function change in the early stage of diabetic retinopathy, and the appropriate results of the cone b-wave, 30-Hz flicker response and PhNR tests are good indicators of moderate NPDR. |
Key Words:
Diabetic retinopathy;Oscillatory potentials;Photopic negative response;Standard electroretinography |
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