The Correlations between Recurrent Disc Hemorrhage and Sympathetic Variability, and the Disc Morphology.

Park, Yi Ryeung; Park, Hae Young Lopilly; Park, Chan Kee

doi:2018.59.2.159

J Korean Ophthalmol Soc > Volume 59(2); 2018 > Article

Original Article

Journal of the Korean Ophthalmological Society 2018;59(2):159-163.
DOI: https://doi.org/10.3341/jkos.2018.59.2.159 Published online February 15, 2018.

The Correlations between Recurrent Disc Hemorrhage and Sympathetic Variability, and the Disc Morphology.

Yi Ryeung Park, Hae Young Lopilly Park, Chan Kee Park

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. ckpark@catholic.ac.kr

반복되는 시신경유두출혈과 자율신경계 변동성 및 시신경 모양과의 연관성

박이령⋅박혜영⋅박찬기

가톨릭대학교 의과대학 서울성모병원 안과 및 시과학교실

Correspondence: Chan Kee Park,
Email: ckpark@catholic.ac.kr

Received: 28 September 2017 • Revised: 11 November 2017 • Accepted: 22 January 2018

Abstract

PURPOSE
To evaluate the correlations of sympathetic variability and recurrent disc hemorrhage, and the morphology of the optic disc. METHODS: This study included 41 eyes of 41 patients who had at least one disc hemorrhage (DH), who were diagnosed with open-angle glaucoma or suspected glaucoma. All eyes had a DH at presentation and were followed-up for at least 3 years. Eyes were classified by the morphology of the optic disc into the focal rim thinning, concentric cupping, or myopic disc groups. The variability of the sympathetic nervous system was defined by the Standard deviation of all node to node intervals (SDNN) as very low frequency, low frequency (LF), or high frequency, which was the standard parameter of heart rate variabilities. RESULTS: There were 14 (34.14%) eyes with a single DH, and the remaining eyes with a recurrent DH. Single DH patients tended to have a myopic disc (p < 0.001) and, especially in the lower 50% of the SDNN group, the recurrent DH group had a lower SDNN (p = 0.046), and a higher LF (p = 0.002). CONCLUSIONS: DH recurred when patients had morphological glaucomatous changes, especially focal rim thinning. Differences of the sympathetic variability had a strong correlation with the recurrent DH.

Key Words: Disc hemorrhage;Hear rate variability;Myopia;Sympathetic