| Experimental Studies of Effects of Ginseng and Steroids on Pneumococcal Endophthalmitis in Rabbits eyes. |
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Yang Su Rim |
1Department of Ophthalmology, National Medical Center, Seoul, Korea.
2Department of OphthalmoIogy, Chung Nam University, Medical SchooI, Tae Jem, Korea. |
| 가토의 폐렴균 안내염에 대한 인삼 및 Steroids 투여의 영향에 관한 실험적 연구 |
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임양수 ( Yang Su Rim ) |
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| Abstract |
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The experimental endophthalmitis was obtained by the injection of pneumococcus into the anterior chamber of the rabbit's eyes and the effects of ginseng and steroids were observed. In one group, ginseng extract (50 mg/kg) was injected intraperitoneally for 6 days. In another group, dexamethasone (0.1 mg/kg) was injected intramuscularly and prednison(R) ophthalmic ointment used topically for 6 days. All groups were treated with atropine and colimycin-T@ ophthalmic ointment topically for 8 days. The eyes were examined clinically and histopathologically. The characteristic pictures of changes of peneumococcal endophthalmitis were stmrnal edema of the cornea by slit lamp biomicroscopic examination. The resuns were as follows: 1. In ginseng injection group, the stromal edema of cornea was more aggravated than control group. 2. In steroids injection group, the stromal edema of cornea was more aggravated than control group. 3. There was no notable difference between the changes in the ginseng injection group and steroids injection group. |
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