J Korean Ophthalmol Soc > Volume 57(8); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(8):1199-1204.
DOI: https://doi.org/10.3341/jkos.2016.57.8.1199    Published online August 15, 2016.
Clinical Effects of Intranasal Steroid Application after Silicone Tube Intubation in Nasolacrimal Duct Obstruction.
Seok Jae Lee, Ho Yoon Kim, Young Min Park, Jong Soo Lee
1Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea. jongsool@pusan.ac.kr
2Department of Ophthalmology, Gyeongsang National University School of Medicine, Jinju, Korea.
3Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Changwon, Korea.
코눈물관 폐쇄에서 실리콘관 삽입술 후 비강 내 스테로이드 분무의 임상적 효과
이석재1⋅김호윤1⋅박영민2,3⋅이종수1
부산대학교 의학전문대학원 안과학교실1, 경상대학교 의학전문대학원 안과학교실2, 창원 경상대학교병원 안과3
Correspondence:  Jong Soo Lee,
Email: jongsool@pusan.ac.kr
Received: 25 February 2016   • Revised: 28 May 2016   • Accepted: 12 July 2016
Abstract
PURPOSE
To investigate the effects of intranasal steroid spray after silicone tube intubation in nasolacrimal duct obstruction. METHODS: We included 73 patients (73 eyes) who had undergone silicone tube intubation with partial nasolacrimal duct obstruction and who had been followed-up for more than 6 months. We divided them into two groups: Group 1 (37 patients, 37 eyes), who used intranasal steroid spray twice a day for 4 weeks after silicone tube intubation, and Group 2 (36 patients, 36 eyes), who did not use intranasal steroid spray. A retrospective medical record review was performed to analyze the clinical features of epiphora improvement and complications in the two groups. RESULTS: No significant difference was found in epiphora improvement after surgery between the two groups (33 eyes [89.2%] in Group 1, 31 eyes [86.1%] in Group 2) (p = 0.736). In addition, the difference in success rate between the two groups was also not statistically significant (33 eyes [89.2%] in Group 1, 28 eyes [77.8%] in Group 2) (p = 0.221). Group 1 (5/37 [13.5%] eyes) and Group 2 (12/36 [33.3%] eyes) complained of ocular discomfort during the period of silicone tube intubation (p = 0.045). The complication rate of Group 1 (5/37 [13.5%] eyes) was significantly lower than that of Group 2 (13/36 [36.1%] eyes) (p = 0.024). CONCLUSIONS: Silicone tube intubation is an effective treatment option for adults diagnosed with partial nasolacrimal duct obstruction, and postoperative intranasal steroid application may contribute to improvement of ocular symptoms after the surgery. There may be a merit of using intranasal steroid spray for adjuvant therapy to prevent postoperative complications, but it needs further study considering various factors.
Key Words: Intranasal steroid spray;Nasolacrimal duct obstruction;Silicone tube intubation


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