Surgical Outcomes of Dacryocystorhinostomy in Lacrimal Drainage Obstruction after Systemic Chemotherapy or Radioactive Iodine Therapy.

Kim, Dong Geun; Lee, Jung Jae; Ham, Dong Sik; Yang, Jae Wook

doi:2016.57.11.1684

J Korean Ophthalmol Soc > Volume 57(11); 2016 > Article

Original Article

Journal of the Korean Ophthalmological Society 2016;57(11):1684-1690.
DOI: https://doi.org/10.3341/jkos.2016.57.11.1684 Published online November 15, 2016.

Surgical Outcomes of Dacryocystorhinostomy in Lacrimal Drainage Obstruction after Systemic Chemotherapy or Radioactive Iodine Therapy.

Dong Geun Kim, Jung Jae Lee, Dong Sik Ham, Jae Wook Yang

¹Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. oculoplasty@gmail.com
²T2B Infrastructure Center for Ocular Disease, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

항암화학요법과 방사성요오드치료 후 발생한 눈물길 폐쇄에서 눈물주머니코안연결술의 시행성적 비교

김동근^1,2⋅이정재^1,2⋅함동식^1,2⋅양재욱^1,2

인제대학교 의과대학 부산백병원 안과학교실¹, 인제대학교 의과대학 부산백병원 안과질환 T2B 기반구축센터²

Abstract

PURPOSE
To compare the outcomes of endonasal dacryocystorhinostomy in patients with secondary lacrimal drainage obstruction associated with systemic chemotherapy or radioactive iodine therapy. METHODS: We retrospectively reviewed the clinical records of patients diagnosed with secondary lacrimal drainage obstruction after systemic chemotherapy or radioactive iodine therapy for thyroid disease and surgical treatment by endonasal dacryocystorhinostomy between January 2009 and January 2015. The control group included randomly selected patients who underwent endonasal dacryocystorhinostomy after diagnosis of primary lacrimal drainage obstruction. RESULTS: Patients were separated into a chemotherapy group (13 eyes of 9 patients), a radioactive iodine therapy group (44 eyes of 32 patients), and a control group (50 eyes of 40 patients). Duration from the onset of systemic chemotherapy or radioactive iodine to the first epiphora symptom was shorter in the chemotherapy group than the radioactive iodine therapy group (p < 0.001). There was no significant difference between the three groups in success rate of endonasal dacryocystorhinostomy. CONCLUSIONS: Most patients with secondary lacrimal drainage obstruction associated with systemic chemotherapy or radioactive iodine therapy had successful outcome of endonasal dacryocystorhinostomy. The success rate of dacryocystorhinostomy was comparable to that in patients with primary lacrimal drainage obstruction.

Key Words: Chemotherapy;Dacryocystorhinostomy;Radioactive iodine;Secondary lacrimal drainage obstruction